Tottenham recovered from losing Harry Kane to a first-half injury to come from behind at Bournemouth and go third in the Premier League.
Kane couldn’t continue after injuring his ankle in a collision with Bournemouth keeper Asmir Begovic shortly before Dele Alli cancelled out Junior Stanislas’ opener for the Cherries.
But Mauricio Pochettino’s side overcame the upset of their Champions League last-16 exit against Juventus on Wednesday, to win convincingly through Son Heung-min’s double and Serge Aurier’s late far-post header.
Bournemouth, who remain 12th, thought they had rescued a point via Callum Wilson’s 84th-minute strike but referee Mike Dean disallowed it for a shove on Spurs defender Davinson Sanchez, before the visitors scored their two late goals.
Alli gave Tottenham fans a scare when he was replaced late on, as did left-back Danny Rose who was making his first top-flight appearance of the year, but both were fatigued rather than injured.
It was Pochettino’s 150th league win as a manager but a rare recent defeat for his counterpart Howe, whose side had been beaten just once in their past 10 league fixtures – only Tottenham losing fewer in that period.